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Synthesis of (2'-5')oligoadenylate and activation of an endoribonuclease in interferon-treated HeLa cells infected with reovirus.

Treatment with interferon protected HeLa cells from infection with reovirus. This virus apparently activated an antiviral mechanism that was detected by the presence of (2'-5')oligoadenylate [(2'-5')An] in intact cells. The (2'-5')An was previously shown to activate an...

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Detaylı Bibliyografya
Asıl Yazarlar: Nilsen, T W, Maroney, P A, Baglioni, C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1982
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC256937/
https://ncbi.nlm.nih.gov/pubmed/6178844
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