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TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection
Cytosine-phosphorothioate-guanine oligodeoxynucleotides (CpG ODNs) are synthetic ODNs with unmethylated DNA sequences that mimic viral and bacterial DNA and protect against infectious agents and tumor challenge. We show that CpG ODNs markedly accelerated graft-versus-host disease (GVHD) lethality by...
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Hematology
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2569186/ https://ncbi.nlm.nih.gov/pubmed/18614760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-113670 |
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