The Novel Mouse Mutation Oblivion Inactivates the PMCA2 Pump and Causes Progressive Hearing Loss

Progressive hearing loss is common in the human population, but we have few clues to the molecular basis. Mouse mutants with progressive hearing loss offer valuable insights, and ENU (N-ethyl-N-nitrosourea) mutagenesis is a useful way of generating models. We have characterised a new ENU-induced mou...

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Autori principali: Spiden, Sarah L., Bortolozzi, Mario, Di Leva, Francesca, de Angelis, Martin Hrabé, Fuchs, Helmut, Lim, Dmitry, Ortolano, Saida, Ingham, Neil J., Brini, Marisa, Carafoli, Ernesto, Mammano, Fabio, Steel, Karen P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568954/
https://ncbi.nlm.nih.gov/pubmed/18974863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000238
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