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A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness
Ca(2+) enters the stereocilia of hair cells through mechanoelectrical transduction channels opened by the deflection of the hair bundle and is exported back to endolymph by an unusual splicing isoform (w/a) of plasma-membrane calcium-pump isoform 2 (PMCA2). Ablation or missense mutations of the pump...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1785272/ https://ncbi.nlm.nih.gov/pubmed/17234811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609775104 |
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