Metabolic Stress Induces the Lysosomal Degradation of Neuropilin-1 but Not Neuropilin-2

The neuropilins-1 and -2 (NRP1 and NRP2) function as receptors for both the semaphorins and vascular endothelial growth factor. In addition to their contribution to the development of the nervous system, NRP1 and NRP2 have been implicated in angiogenesis and tumor progression. Given their importance...

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Bibliographic Details
Main Authors: Bae, Donggoo, Lu, Shaolei, Taglienti, Cherie A., Mercurio, Arthur M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Molecular Basis of Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568914/
https://ncbi.nlm.nih.gov/pubmed/18708346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804203200
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