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Identification and Functional Characterization of an N-terminal Oligomerization Domain for Polycystin-2
Autosomal dominant polycystic kidney disease (ADPKD), the most common inherited cause of kidney failure, is caused by mutations in either PKD1 (85%) or PKD2 (15%). The PKD2 protein, polycystin-2 (PC2 or TRPP2), is a member of the transient receptor potential (TRP) superfamily and functions as a non-...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2568912/ https://ncbi.nlm.nih.gov/pubmed/18701462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803834200 |
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