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Dibutyltin Disrupts Glucocorticoid Receptor Function and Impairs Glucocorticoid-Induced Suppression of Cytokine Production

BACKGROUND: Organotins are highly toxic and widely distributed environmental chemicals. Dibutyltin (DBT) is used as stabilizer in the production of polyvinyl chloride plastics, and it is also the major metabolite formed from tributyltin (TBT) in vivo. DBT is immunotoxic, however, the responsible tar...

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Detalhes bibliográficos
Main Authors: Gumy, Christel, Chandsawangbhuwana, Charlie, Dzyakanchuk, Anna A., Kratschmar, Denise V., Baker, Michael E., Odermatt, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568824/
https://ncbi.nlm.nih.gov/pubmed/18958157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003545
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