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Dibutyltin Disrupts Glucocorticoid Receptor Function and Impairs Glucocorticoid-Induced Suppression of Cytokine Production

BACKGROUND: Organotins are highly toxic and widely distributed environmental chemicals. Dibutyltin (DBT) is used as stabilizer in the production of polyvinyl chloride plastics, and it is also the major metabolite formed from tributyltin (TBT) in vivo. DBT is immunotoxic, however, the responsible tar...

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Bibliografische gegevens
Hoofdauteurs: Gumy, Christel, Chandsawangbhuwana, Charlie, Dzyakanchuk, Anna A., Kratschmar, Denise V., Baker, Michael E., Odermatt, Alex
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568824/
https://ncbi.nlm.nih.gov/pubmed/18958157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003545
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