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Structural analysis of the evolution of steroid specificity in the mineralocorticoid and glucocorticoid receptors
BACKGROUND: The glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) evolved from a common ancestor. Still not completely understood is how specificity for glucocorticoids (e.g. cortisol) and mineralocorticoids (e.g. aldosterone) evolved in these receptors. RESULTS: Our analysis of sever...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1805736/ https://ncbi.nlm.nih.gov/pubmed/17306029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-24 |
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