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Isolation and preliminary characterization of temperature-sensitive mutants of poliovirus type 1.
We isolated six temperature-sensitive mutants of poliovirus type 1 (Mahoney) by hydroxylamine mutagenesis and replica plating at 31, 33 (permissive), and 39 degrees C (restrictive). One of these mutants, designated tsB9, was chosen for more detailed examination. tsB9 accumulated 25% of the wild-type...
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| Gepubliceerd in: | J Virol |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology (ASM)
1982
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256848/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6284963/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.41.3.1089-1094.1982 |
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