Increased efficacy of phosphonoformate and phosphonoacetate inhibition of herpes simplex virus type 2 replication by encapsulation in liposomes.

Phosphonoformate and phosphonoacetate encapsulated in liposomes have substantially greater activity against herpes simplex virus type 2 in Vero cell tissue culture than the nonencapsulated compounds at the same dose. Encapsulation of phosphonoformate in liposomes resulted in a 30-fold increase of th...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Szoka, F C, Chu, C J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172296/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2843083/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.6.858
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