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Increased efficacy of phosphonoformate and phosphonoacetate inhibition of herpes simplex virus type 2 replication by encapsulation in liposomes.

Phosphonoformate and phosphonoacetate encapsulated in liposomes have substantially greater activity against herpes simplex virus type 2 in Vero cell tissue culture than the nonencapsulated compounds at the same dose. Encapsulation of phosphonoformate in liposomes resulted in a 30-fold increase of th...

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Detalles Bibliográficos
Main Authors: Szoka, F C, Chu, C J
Formato: Artigo
Idioma:Inglês
Publicado: 1988
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC172296/
https://ncbi.nlm.nih.gov/pubmed/2843083
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