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Automatic detection of exonic splicing enhancers (ESEs) using SVMs

BACKGROUND: Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for SR proteins. To study the impact of ESEs on alternative splicing it would be useful to have a possibility to detect them i...

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Main Authors: Mersch, Britta, Gepperth, Alexander, Suhai, Sándor, Hotz-Wagenblatt, Agnes
格式: Artigo
語言:Inglês
出版: BioMed Central 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567995/
https://ncbi.nlm.nih.gov/pubmed/18783607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-369
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