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Automatic detection of exonic splicing enhancers (ESEs) using SVMs

BACKGROUND: Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for SR proteins. To study the impact of ESEs on alternative splicing it would be useful to have a possibility to detect them i...

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Auteurs principaux: Mersch, Britta, Gepperth, Alexander, Suhai, Sándor, Hotz-Wagenblatt, Agnes
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567995/
https://ncbi.nlm.nih.gov/pubmed/18783607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-369
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