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Coevolution of Function and the Folding Landscape: Correlation with Density of Native Contacts
The relationship between the folding landscape and function of evolved proteins is explored by comparison of the folding mechanisms for members of the flavodoxin fold. CheY, Spo0F, and NtrC have unrelated functions and low sequence homology but share an identical topology. Recent coarse-grained simu...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567933/ https://ncbi.nlm.nih.gov/pubmed/18708465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.143388 |
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