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Biophysical Studies on the Stability of DNA Intrastrand Cross-Links of Transplatin

Clinically ineffective transplatin [trans-diamminedichloridoplatinum(II)] is used in the studies of the structure-pharmacological activity relationship of platinum compounds. In addition, a number of transplatin analogs exhibit promising toxic effects in several tumor cell lines including those resi...

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Main Authors: Kasparkova, Jana, Marini, Victoria, Bursova, Vendula, Brabec, Viktor
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567932/
https://ncbi.nlm.nih.gov/pubmed/18676645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.138909
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