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Molecular Dynamics Simulations of GABA Binding to the GABA(C) Receptor: The Role of Arg(104)

GABA is the major inhibitory neurotransmitter in the nervous system and acts at a variety of receptors including GABA(C) receptors, which are a subclass of GABA(A) receptors. Here we have used molecular dynamics simulations of GABA docked into the extracellular domain of the GABA(C) receptor to expl...

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Detalhes bibliográficos
Main Authors: Melis, Claudio, Lummis, Sarah C. R., Molteni, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567930/
https://ncbi.nlm.nih.gov/pubmed/18641081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.127589
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