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A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

Recognition sites for microRNAs (miRNAs) have been reported to be located in the 3′ untranslated regions of transcripts. In a computational screen for highly conserved motifs within coding regions, we found an excess of sequences conserved at the nucleotide level within coding regions in the human g...

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Autori principali: Forman, Joshua J., Legesse-Miller, Aster, Coller, Hilary A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567461/
https://ncbi.nlm.nih.gov/pubmed/18812516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803230105
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