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Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution

BACKGROUND: Most human endogenous retroviruses (HERVs) invaded our genome at least 25 million years ago. The majority of the viral genes are degenerated, since no selection preserves them within the genome. However, a few intact and very old HERV genes exist, and likely are beneficial for the host....

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Hlavní autoři: Kjeldbjerg, Anders L, Villesen, Palle, Aagaard, Lars, Pedersen, Finn Skou
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567338/
https://ncbi.nlm.nih.gov/pubmed/18826608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-266
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