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Silencing of endogenous envelope genes in human choriocarcinoma cells shows that envPb1 is involved in heterotypic cell fusions

Syncytin-1 and envPb1 are two conserved envelope genes in the human genome encoded by single loci from the HERV-W and -Pb families, respectively. To characterize the role of these envelope proteins in cell–cell fusion, we have developed lentiviral vectors that express short hairpin RNAs for stable k...

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Detalhes bibliográficos
Main Authors: Aagaard, Lars, Bjerregaard, Bolette, Kjeldbjerg, Anders L., Pedersen, Finn Skou, Larsson, Lars-Inge, Rossi, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541762/
https://ncbi.nlm.nih.gov/pubmed/22573740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.041764-0
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