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An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo
Murine leukemia viruses harboring an internal ribosome entry site (IRES)-directed translational cassette are able to replicate, but undergo loss of heterologous sequences upon continued passage. While complete loss of heterologous sequences is favored when these are flanked by a direct repeat, delet...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390364/ https://ncbi.nlm.nih.gov/pubmed/15069126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh513 |
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