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An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo

Murine leukemia viruses harboring an internal ribosome entry site (IRES)-directed translational cassette are able to replicate, but undergo loss of heterologous sequences upon continued passage. While complete loss of heterologous sequences is favored when these are flanked by a direct repeat, delet...

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Detalhes bibliográficos
Main Authors: Duch, Mogens, Carrasco, Maria L., Jespersen, Thomas, Aagaard, Lars, Pedersen, Finn Skou
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC390364/
https://ncbi.nlm.nih.gov/pubmed/15069126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh513
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