Upregulated HSP27 in human breast cancer cells reduces Herceptin susceptibility by increasing Her2 protein stability

BACKGROUND: Elucidating the molecular mechanisms by which tumors become resistant to Herceptin is critical for the treatment of Her2-overexpressed metastatic breast cancer. METHODS: To further understand Herceptin resistance mechanisms at the molecular level, we used comparative proteome approaches...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kang, Se Hun, Kang, Keon Wook, Kim, Kyung-Hee, Kwon, Bumi, Kim, Seok-Ki, Lee, Ho-Young, Kong, Sun-Young, Lee, Eun Sook, Jang, Sang-Geun, Yoo, Byong Chul
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567332/
https://ncbi.nlm.nih.gov/pubmed/18834540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-286
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados