Purinergic receptors contribute to early mesangial cell transformation and renal vessel hypertrophy during angiotensin II-induced hypertension

Chronic ANG II infusions lead to increases in intrarenal ANG II levels, hypertension, and tissue injury. Increased blood pressure also elicits increases in renal interstitial fluid (RIF) ATP concentrations that stimulate cell proliferation. We evaluated the contribution of purinergic receptor activa...

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Hlavní autoři: Graciano, Miguel L., Nishiyama, Akira, Jackson, Keith, Seth, Dale M., Ortiz, Rudy M., Prieto-Carrasquero, Minolfa C., Kobori, Hiroyuki, Navar, L. Gabriel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567285/
https://ncbi.nlm.nih.gov/pubmed/17989111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00281.2007
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