Purinergic receptors contribute to early mesangial cell transformation and renal vessel hypertrophy during angiotensin II-induced hypertension

Chronic ANG II infusions lead to increases in intrarenal ANG II levels, hypertension, and tissue injury. Increased blood pressure also elicits increases in renal interstitial fluid (RIF) ATP concentrations that stimulate cell proliferation. We evaluated the contribution of purinergic receptor activa...

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Bibliographic Details
Main Authors: Graciano, Miguel L., Nishiyama, Akira, Jackson, Keith, Seth, Dale M., Ortiz, Rudy M., Prieto-Carrasquero, Minolfa C., Kobori, Hiroyuki, Navar, L. Gabriel
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567285/
https://ncbi.nlm.nih.gov/pubmed/17989111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00281.2007
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