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Purinergic receptors contribute to early mesangial cell transformation and renal vessel hypertrophy during angiotensin II-induced hypertension

Chronic ANG II infusions lead to increases in intrarenal ANG II levels, hypertension, and tissue injury. Increased blood pressure also elicits increases in renal interstitial fluid (RIF) ATP concentrations that stimulate cell proliferation. We evaluated the contribution of purinergic receptor activa...

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Détails bibliographiques
Auteurs principaux: Graciano, Miguel L., Nishiyama, Akira, Jackson, Keith, Seth, Dale M., Ortiz, Rudy M., Prieto-Carrasquero, Minolfa C., Kobori, Hiroyuki, Navar, L. Gabriel
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567285/
https://ncbi.nlm.nih.gov/pubmed/17989111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00281.2007
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