Structural determinants for membrane association and dynamic organization of the hepatitis C virus NS3-4A complex

Hepatitis C virus (HCV) NS3-4A is a membrane-associated multifunctional protein harboring serine protease and RNA helicase activities. It is an essential component of the HCV replication complex and a prime target for antiviral intervention. Here, we show that membrane association and structural org...

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Hlavní autoři: Brass, Volker, Berke, Jan Martin, Montserret, Roland, Blum, Hubert E., Penin, François, Moradpour, Darius
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567209/
https://ncbi.nlm.nih.gov/pubmed/18799730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807298105
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