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Increased Potency and Longevity of Gene Silencing Using Validated Dicer Substrates

Chemically synthesized small interfering RNAs (siRNAs) are tools used for silencing the expression of a single gene. They are mainly employed in basic research applications, but may also have great potential in therapeutic applications. Longer double-stranded RNAs, such as Dicer-substrate 27mers, tr...

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Detalhes bibliográficos
Main Authors: Hefner, E., Clark, K., Whitman, C., Behlke, M.A., Rose, S.D., Peek, A.S., Rubio, T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association of Biomolecular Resource Facilities 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567136/
https://ncbi.nlm.nih.gov/pubmed/19137112
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