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Structure of the Escherichia coli ThiS-ThiF complex, a key component of the sulfur transfer system in thiamin biosynthesis

We have determined the crystal structure of the Escherichia coli ThiS-ThiF protein complex at 2.0 Å resolution. ThiS and ThiF are bacterial proteins involved in the synthesis of the thiazole moiety of thiamin. ThiF catalyzes the adenylation of the carboxy terminus of ThiS and the subsequent displace...

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Autors principals: Lehmann, Christopher, Begley, Tadhg P., Ealick, Steven E.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566941/
https://ncbi.nlm.nih.gov/pubmed/16388576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051502y
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