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Protein–DNA interactions: structural, thermodynamic and clustering patterns of conserved residues in DNA-binding proteins
Amino acid residues, which play important roles in protein function, are often conserved. Here, we analyze thermodynamic and structural data of protein–DNA interactions to explore a relationship between free energy, sequence conservation and structural cooperativity. We observe that the most stabili...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2566867/ https://ncbi.nlm.nih.gov/pubmed/18801847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn573 |
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