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Restricted Mobility of Conserved Residues in Protein-Protein Interfaces in Molecular Simulations
Conserved residues in protein-protein interfaces correlate with residue hot-spots. To obtain insight into their roles, we have studied their mobility. We have performed 39 explicit solvent simulations of 15 complexes and their monomers, with the interfaces varying in size, shape, and function. The d...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292389/ https://ncbi.nlm.nih.gov/pubmed/18227135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.114835 |
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