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Characterization of Human Aspartoacylase: the brain enzyme responsible for Canavan disease
Aspartoacylase catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate, and is the only brain enzyme that has been shown to effectively metabolize NAA. Although the exact role of this enzymatic reaction has not yet been completely elucidated, the metabolism of N...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2566822/ https://ncbi.nlm.nih.gov/pubmed/16669630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052608w |
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