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Characterization of Human Aspartoacylase: the brain enzyme responsible for Canavan disease

Aspartoacylase catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate, and is the only brain enzyme that has been shown to effectively metabolize NAA. Although the exact role of this enzymatic reaction has not yet been completely elucidated, the metabolism of N...

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Hlavní autoři: Le Coq, Johanne, An, Hyun-Joo, Lebrilla, Carlito, Viola, Ronald E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566822/
https://ncbi.nlm.nih.gov/pubmed/16669630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052608w
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