MyD88 Dependent Signaling Contributes to Protective Host Defense against Burkholderia pseudomallei

BACKGROUND: Toll-like receptors (TLRs) have a central role in the recognition of pathogens and the initiation of the innate immune response. Myeloid differentiation primary-response gene 88 (MyD88) and TIR-domain-containing adaptor protein inducing IFNβ (TRIF) are regarded as the key signaling adapt...

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Bibliographic Details
Main Authors: Wiersinga, W. Joost, Wieland, Catharina W., Roelofs, Joris J. T. H., van der Poll, Tom
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566818/
https://ncbi.nlm.nih.gov/pubmed/18946505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003494
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