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The Long March: A Sample Preparation Technique that Enhances Contig Length and Coverage by High-Throughput Short-Read Sequencing

High-throughput short-read technologies have revolutionized DNA sequencing by drastically reducing the cost per base of sequencing information. Despite producing gigabases of sequence per run, these technologies still present obstacles in resequencing and de novo assembly applications due to biased...

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Detalhes bibliográficos
Main Authors: Sorber, Katherine, Chiu, Charles, Webster, Dale, Dimon, Michelle, Ruby, J. Graham, Hekele, Armin, DeRisi, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566813/
https://ncbi.nlm.nih.gov/pubmed/18941527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003495
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