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Read length versus Depth of Coverage for Viral Quasispecies Reconstruction

Recent advancements of sequencing technology have opened up unprecedented opportunities in many application areas. Virus samples can now be sequenced efficiently with very deep coverage to infer the genetic diversity of the underlying virus populations. Several sequencing platforms with different un...

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Detalhes bibliográficos
Main Authors: Zagordi, Osvaldo, Däumer, Martin, Beisel, Christian, Beerenwinkel, Niko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463535/
https://ncbi.nlm.nih.gov/pubmed/23056573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047046
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