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Neuronal Calcium Mishandling and the Pathogenesis of Alzheimer’s Disease

Perturbed neuronal Ca(2+) homeostasis is implicated in age-related cognitive impairment and Alzheimer’s disease (AD). With advancing age neurons encounter increased oxidative stress and impaired energy metabolism, which compromise the function of proteins that control membrane excitability and subce...

詳細記述

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書誌詳細
主要な著者: Bezprozvanny, Ilya, Mattson, Mark P.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566585/
https://ncbi.nlm.nih.gov/pubmed/18675468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2008.06.005
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