Impaired Hepatitis C Virus (HCV)-Specific Effector CD8(+) T Cells Undergo Massive Apoptosis in the Peripheral Blood during Acute HCV Infection and in the Liver during the Chronic Phase of Infection

A majority of patients infected with hepatitis C virus (HCV) do not sustain an effective T-cell response, and viremia persists. The mechanism leading to failure of the HCV-specific CD8(+) T-cell response in patients developing chronic infection is unclear. We investigated apoptosis susceptibility of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Radziewicz, Henry, Ibegbu, Chris C., Hon, Huiming, Osborn, Melissa K., Obideen, Kamil, Wehbi, Mohammad, Freeman, Gordon J., Lennox, Jeffrey L., Workowski, Kimberly A., Hanson, Holly L., Grakoui, Arash
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566282/
https://ncbi.nlm.nih.gov/pubmed/18667503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01075-08
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados