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Cell Cycle-Independent Expression of Immediate-Early Gene 3 Results in G(1) and G(2) Arrest in Murine Cytomegalovirus-Infected Cells
The infectious cycle of human cytomegalovirus (HCMV) is intricately linked to the host's cell cycle. Viral gene expression can be initiated only in G(0)/G(1) phase. Once expressed, the immediate-early gene product IE2 prevents cellular DNA synthesis, arresting infected cells with a G(1) DNA con...
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主要な著者: | , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Society for Microbiology (ASM)
2008
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2566281/ https://ncbi.nlm.nih.gov/pubmed/18667506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01212-08 |
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