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Hydroxymethylnitrofurazone:Dimethyl-β-cyclodextrin Inclusion Complex: A Physical–Chemistry Characterization

Hydroxymethylnitrofurazone (NFOH) is active against Trypanosoma cruzi; however, its low solubility and high toxicity precludes its current use in treatment of parasitosis. Cyclodextrin can be used as a drug carrier system, as it is able to form inclusion (host–guest) complexes with a wide variety of...

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Detalhes bibliográficos
Main Authors: Grillo, Renato, Melo, Nathalie Ferreira Silva, Moraes, Carolina Morales, Rosa, André Henrique, Roveda, José Arnaldo Frutuoso, Menezes, Carla M. S., Ferreira, Elizabeth Igne, Fraceto, Leonardo Fernandes
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565764/
https://ncbi.nlm.nih.gov/pubmed/19669530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-008-9054-7
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