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Palladium Asymmetric Allylic Alkylation of Prochiral Nucleophiles: Horsfiline

[Image: see text] The asymmetric synthesis of the oxindole alkaloid horsfiline is described. A palladium-catalyzed asymmetric allylic alkylation (AAA) is used to set the spiro(pyrrolidine-oxindole) stereogenic center.

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Bibliografiske detaljer
Main Authors: M.Trost, Barry, Brennan, Megan K.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565574/
https://ncbi.nlm.nih.gov/pubmed/16671773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol060298j
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