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Exploiting the Pd- and Ru-Catalyzed Cycloisomerizations: Enantioselective Total Synthesis of (+)-Allocyathin B(2)

Pd and Ru catalyzed cycloisomerizations of 1,6-enynes are compared and contrasted. Such considerations led to the enantioselective synthesis of a cyathin terpenoid, (+)-allocyathin B(2) (1). The synthesis features a Pd-catalyzed asymmetric allylic alkylation (AAA) to install the initial quaternary c...

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Detalhes bibliográficos
Main Authors: Trost, Barry M., Dong, Li, Schroeder, Gretchen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565572/
https://ncbi.nlm.nih.gov/pubmed/16028937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja051547m
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