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Exploiting the Pd- and Ru-Catalyzed Cycloisomerizations: Enantioselective Total Synthesis of (+)-Allocyathin B(2)

Pd and Ru catalyzed cycloisomerizations of 1,6-enynes are compared and contrasted. Such considerations led to the enantioselective synthesis of a cyathin terpenoid, (+)-allocyathin B(2) (1). The synthesis features a Pd-catalyzed asymmetric allylic alkylation (AAA) to install the initial quaternary c...

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Autors principals: Trost, Barry M., Dong, Li, Schroeder, Gretchen M.
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565572/
https://ncbi.nlm.nih.gov/pubmed/16028937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja051547m
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