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Evidence for Restriction of Ancient Primate Gammaretroviruses by APOBEC3 but Not TRIM5α Proteins

Because of evolutionary pressures imposed through episodic colonization by retroviruses, many mammals express factors, such as TRIM5α and APOBEC3 proteins, that directly restrict retroviral replication. TRIM5 and APOBEC restriction factors are most often studied in the context of modern primate lent...

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Detalhes bibliográficos
Main Authors: Perez-Caballero, David, Soll, Steven J., Bieniasz, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564838/
https://ncbi.nlm.nih.gov/pubmed/18927623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000181
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