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Survivin‐directed RNA interference cocktail is a potent suppressor of tumour growth in vivo

BACKGROUND: Survivin is proposed to play a central role in the progression and resistance to therapy of diverse tumour types. High levels of this molecule in tumour cells also correlate with loss of the TP53 tumour suppressor gene, suggesting a molecular connection between TP53 loss and transcriptio...

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Библиографические подробности
Главные авторы: Caldas, H, Holloway, M P, Hall, B M, Qualman, S J, Altura, R A
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Group 2006
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564625/
https://ncbi.nlm.nih.gov/pubmed/15908567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.034686
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