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Oncolytic adenovirus mediated Survivin knockdown by RNA interference suppresses human colorectal carcinoma growth in vitro and in vivo

BACKGROUND: Colorectal cancer is a one of the most common alimentary malignancies. Survivin has been proved by many studies to be an ideal target for cancer gene therapy because of its strong anti-apoptotic effect. The reduction of Survivin expression by means of chemically synthesized small interfe...

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Hlavní autoři: Shen, Wei, Wang, Chun-Yi, Wang, Xue-Hu, Fu, Zhong-Xue
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703625/
https://ncbi.nlm.nih.gov/pubmed/19527508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-28-81
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