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Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

How organ size is controlled in mammals is not currently understood. In Drosophila the Hippo signaling pathway functions to suppress growth in imaginal discs and has been suggested to control organ size. To investigate the role of hippo signaling in regulation of mammalian organ size we have generat...

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Detalhes bibliográficos
Main Authors: Lu, Li, Li, Ying, Kim, Soo Mi, Bossuyt, Wouter, Liu, Pu, Qiu, Qiong, Wang, Yingdi, Halder, Georg, Finegold, Milton J., Lee, Ju-Seog, Johnson, Randy L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824398/
https://ncbi.nlm.nih.gov/pubmed/20080689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911427107
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