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Predicting disease genes using protein–protein interactions

BACKGROUND: The responsible genes have not yet been identified for many genetically mapped disease loci. Physically interacting proteins tend to be involved in the same cellular process, and mutations in their genes may lead to similar disease phenotypes. OBJECTIVE: To investigate whether protein–pr...

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Detaylı Bibliyografya
Asıl Yazarlar: Oti, M, Snel, B, Huynen, M A, Brunner, H G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Group 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564594/
https://ncbi.nlm.nih.gov/pubmed/16611749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.041376
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