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Predicting disease genes using protein–protein interactions
BACKGROUND: The responsible genes have not yet been identified for many genetically mapped disease loci. Physically interacting proteins tend to be involved in the same cellular process, and mutations in their genes may lead to similar disease phenotypes. OBJECTIVE: To investigate whether protein–pr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Group
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2564594/ https://ncbi.nlm.nih.gov/pubmed/16611749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.041376 |
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