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Conserved co-expression for candidate disease gene prioritization

BACKGROUND: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between genes. The evolutionary conservation of co-expression between species can be used to predict protein function more reliably...

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Detalhes bibliográficos
Main Authors: Oti, Martin, van Reeuwijk, Jeroen, Huynen, Martijn A, Brunner, Han G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2383918/
https://ncbi.nlm.nih.gov/pubmed/18433471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-208
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