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Altered CD45 expression in C77G carriers influences immune function and outcome of hepatitis C infection

BACKGROUND: A polymorphism in exon 4 (C77G) of CD45 that alters CD45 splicing has been associated with autoimmune and infectious diseases in humans. OBJECTIVE: To investigate the effect of C77G in hepatitis C virus (HCV) infected individuals and study the phenotype and function of peripheral blood m...

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Autori principali: Dawes, R, Hennig, B, Irving, W, Petrova, S, Boxall, S, Ward, V, Wallace, D, Macallan, D C, Thursz, M, Hill, A, Bodmer, W, Beverley, P C L, Tchilian, E Z
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564592/
https://ncbi.nlm.nih.gov/pubmed/16505159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.040485
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