CD45 negatively regulates tumour necrosis factor and interleukin-6 production in dendritic cells

CD45 is known to regulate signalling through many different surface receptors in diverse haemopoietic cell types. Here we report for the first time that CD45(−/−) bone marrow dendritic cells (BMDC) are more activated than CD45(+/+) cells and that tumour necrosis factor (TNF) and interleukin-6 (IL-6)...

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Detalhes bibliográficos
Main Authors: Piercy, Jenny, Petrova, Svetla, Tchilian, Elma Z, Beverley, Peter C L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782285/
https://ncbi.nlm.nih.gov/pubmed/16771860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02363.x
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