Regulation of dendritic cell interleukin-12 secretion by tumour cell necrosis

Dendritic cells (DCs) play a key role in the induction and regulation of antigen-specific immunity. Studies have shown that, similar to infection, cellular necrosis can stimulate DC maturation. However, the ability of necrotic cell death to modulate DC cytokine secretion has yet to be explored. We i...

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Bibliographic Details
Main Authors: Kandil, H, Bachy, V, Williams, D J, Helmi, R, Gotch, F M, Ibrahim, M A A
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2005
Subjects:
Basic Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809329/
https://ncbi.nlm.nih.gov/pubmed/15762875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02730.x
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